Conquistando Escalones makes a payment of €10,000 to continue research at the University of Bologna

The team led by Prof. Cenacchi, from the Department of Biomedical and Neuromotor Sciences of the University of Bologna, is one of the research groups that seeks to achieve a treatment and/or cure for our Limb-girdle Muscular Dystrophy 1F/D2.

We have just made a payment of €10,000 to the Department of Biomedical and Neuromotor Sciences of the University of Bologna, as co-financing of the project “Functional characterization of Transportin 3 in myogenic differentiation in cell and animal models (Zebrafish) of Limb-girdle Muscular Dystrophy 1F/D2”.

From the beginning, the main objective of the team led by Prof. Cenacchi has been to clarify the role of Transportin 3 (TNPO3) (our mutated protein) in skeletal muscle both under normal conditions and in the case of our Limb-girdle Muscular Dystrophy 1F.

Specifically, with our new funding for the project, researcher María Teresa Rodia tells us that:

“The aim of the study is to use the Zebrafish animal and cell model using cells of human and mouse muscle origin to clarify the role of TNPO3 in myogenic differentiation and in the pathogenesis of LGMDD2. The data obtained from this experimental study may lead us to identify alterations in the expression of proteins involved in TNPO3-dependent molecular mechanisms, contributing to clarify the role of TNPO3 in myogenic differentiation and in the pathogenesis of LGMDD2.”

As always, we emphasize that the times of science are not as fast as we all would like. But they have some necessary steps so that the work done is not in vain and that it can be applied to humans with confidence in the results and without danger to them.

We want to thank Prof. Cenacchi, and her entire group, for all her work and dedication inside and outside the laboratory. As well as her personal involvement beyond professional and all her efforts towards the investigation of this particular form of Limb-Girdle Muscular Dystrophy.